Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Identifieur interne : 000640 ( Main/Exploration ); précédent : 000639; suivant : 000641Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
Auteurs : Edward Burn [Espagne, Royaume-Uni] ; Seng Chan You [Corée du Sud] ; Anthony G. Sena [États-Unis, Pays-Bas] ; Kristin Kostka [États-Unis] ; Hamed Abedtash [États-Unis] ; Maria Tereza F. Abrahão [Brésil] ; Amanda Alberga [Canada] ; Heba Alghoul ; Osaid Alser [États-Unis] ; Thamir M. Alshammari [Arabie saoudite] ; Maria Aragon [Espagne] ; Carlos Areia [Royaume-Uni] ; Juan M. Banda [États-Unis] ; Jaehyeong Cho [Corée du Sud] ; Aedin C. Culhane [États-Unis] ; Alexander Davydov [États-Unis, Biélorussie] ; Frank J. Defalco [États-Unis] ; Talita Duarte-Salles [Espagne] ; Scott Duvall [États-Unis] ; Thomas Falconer [États-Unis] ; Sergio Fernandez-Bertolin [Espagne] ; Weihua Gao [États-Unis] ; Asieh Golozar [États-Unis] ; Jill Hardin [États-Unis] ; George Hripcsak [États-Unis] ; Vojtech Huser [États-Unis] ; Hokyun Jeon [Corée du Sud] ; Yonghua Jing [États-Unis] ; Chi Young Jung [Corée du Sud] ; Benjamin Skov Kaas-Hansen [Danemark] ; Denys Kaduk [États-Unis, Ukraine] ; Seamus Kent [Royaume-Uni] ; Yeesuk Kim [Corée du Sud] ; Spyros Kolovos [Royaume-Uni] ; Jennifer C E. Lane [Royaume-Uni] ; Hyejin Lee [Corée du Sud] ; Kristine E. Lynch [États-Unis] ; Rupa Makadia [États-Unis] ; Michael E. Matheny [États-Unis] ; Paras P. Mehta [États-Unis] ; Daniel R. Morales [Royaume-Uni] ; Karthik Natarajan [États-Unis] ; Fredrik Nyberg [Suède] ; Anna Ostropolets [États-Unis] ; Rae Woong Park [Corée du Sud] ; Jimyung Park [Corée du Sud] ; Jose D. Posada [États-Unis] ; Albert Prats-Uribe [Royaume-Uni] ; Gowtham Rao [États-Unis] ; Christian Reich [États-Unis] ; Yeunsook Rho [Royaume-Uni] ; Peter Rijnbeek [Pays-Bas] ; Lisa M. Schilling [États-Unis] ; Martijn Schuemie [États-Unis] ; Nigam H. Shah [États-Unis] ; Azza Shoaibi [États-Unis] ; Seokyoung Song [Corée du Sud] ; Matthew Spotnitz [États-Unis] ; Marc A. Suchard [États-Unis] ; Joel N. Swerdel [États-Unis] ; David Vizcaya [Espagne] ; Salvatore Volpe [États-Unis] ; Haini Wen [République populaire de Chine] ; Andrew E. Williams [États-Unis] ; Belay B. Yimer [Royaume-Uni] ; Lin Zhang [République populaire de Chine, Australie] ; Oleg Zhuk [États-Unis] ; Daniel Prieto-Alhambra [Royaume-Uni] ; Patrick Ryan [États-Unis]Source :
- Nature communications [ 2041-1723 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Comorbidité (MeSH), Espagne (épidémiologie), Facteurs sexuels (MeSH), Facteurs âges (MeSH), Femelle (MeSH), Grippe humaine (traitement médicamenteux), Grippe humaine (épidémiologie), Hospitalisation (MeSH), Humains (MeSH), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (épidémiologie), Jeune adulte (MeSH), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (traitement médicamenteux), Pneumopathie virale (épidémiologie), Prévalence (MeSH), République de Corée (épidémiologie), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), États-Unis (épidémiologie), Études de cohortes (MeSH).
- MESH :
- traitement médicamenteux : Grippe humaine, Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Espagne, Grippe humaine, Infections à coronavirus, Pneumopathie virale, République de Corée, États-Unis.
- Adulte, Adulte d'âge moyen, Comorbidité, Facteurs sexuels, Facteurs âges, Femelle, Hospitalisation, Humains, Jeune adulte, Mâle, Pandémies, Prévalence, Sujet âgé, Sujet âgé de 80 ans ou plus, Études de cohortes.
- Wicri :
- geographic : Espagne, États-Unis.
English descriptors
- KwdEn :
- Adult (MeSH), Age Factors (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), COVID-19 (MeSH), Cohort Studies (MeSH), Comorbidity (MeSH), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Female (MeSH), Hospitalization (MeSH), Humans (MeSH), Influenza, Human (drug therapy), Influenza, Human (epidemiology), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (drug therapy), Pneumonia, Viral (epidemiology), Prevalence (MeSH), Republic of Korea (epidemiology), Sex Factors (MeSH), Spain (epidemiology), United States (epidemiology), Young Adult (MeSH).
- MESH :
- geographic , epidemiology : Republic of Korea, Spain, United States.
- drug therapy : Coronavirus Infections, Influenza, Human, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Influenza, Human, Pneumonia, Viral.
- Adult, Age Factors, Aged, Aged, 80 and over, COVID-19, Cohort Studies, Comorbidity, Female, Hospitalization, Humans, Male, Middle Aged, Pandemics, Prevalence, Sex Factors, Young Adult.
Abstract
Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19.
DOI: 10.1038/s41467-020-18849-z
PubMed: 33024121
PubMed Central: PMC7538555
Affiliations:
- Arabie saoudite, Australie, Biélorussie, Brésil, Canada, Corée du Sud, Danemark, Espagne, Pays-Bas, Royaume-Uni, République populaire de Chine, Suède, Ukraine, États-Unis
- Angleterre, Arizona, Californie, Catalogne, Colorado, Grand Londres, Grand Manchester, Géorgie (États-Unis), Hollande-Méridionale, Hovedstaden, Illinois, Indiana, Maryland, Massachusetts, New Jersey, Oxfordshire, Région capitale de Séoul, Tennessee, Utah, Victoria (État), État de New York, État de São Paulo
- Barcelone, Copenhague, Londres, Manchester, Melbourne, New York, Oxford, Pékin, Rotterdam, Stanford (Californie), São Paulo, Séoul
- Université Columbia, Université Stanford, Université d'Oxford, Université de Manchester, Université de Melbourne, Université de São Paulo
Links toward previous steps (curation, corpus...)
Le document en format XML
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Alshammari</name><affiliation wicri:level="1"><nlm:affiliation>Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Medication Safety Research Chair, King Saud University, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Aragon, Maria" sort="Aragon, Maria" uniqKey="Aragon M" first="Maria" last="Aragon">Maria Aragon</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Areia, Carlos" sort="Areia, Carlos" uniqKey="Areia C" first="Carlos" last="Areia">Carlos Areia</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Banda, Juan M" sort="Banda, Juan M" uniqKey="Banda J" first="Juan M" last="Banda">Juan M. Banda</name><affiliation wicri:level="2"><nlm:affiliation>Department of Computer Science, Georgia State University, Atlanta, GA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Georgia State University, Atlanta, GA</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Cho, Jaehyeong" sort="Cho, Jaehyeong" uniqKey="Cho J" first="Jaehyeong" last="Cho">Jaehyeong Cho</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Culhane, Aedin C" sort="Culhane, Aedin C" uniqKey="Culhane A" first="Aedin C" last="Culhane">Aedin C. 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Biostatistics, Harvard TH Chan School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Davydov, Alexander" sort="Davydov, Alexander" uniqKey="Davydov A" first="Alexander" last="Davydov">Alexander Davydov</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk, Belarus.</nlm:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Defalco, Frank J" sort="Defalco, Frank J" uniqKey="Defalco F" first="Frank J" last="Defalco">Frank J. Defalco</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Duarte Salles, Talita" sort="Duarte Salles, Talita" uniqKey="Duarte Salles T" first="Talita" last="Duarte-Salles">Talita Duarte-Salles</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Duvall, Scott" sort="Duvall, Scott" uniqKey="Duvall S" first="Scott" last="Duvall">Scott Duvall</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterans Affairs, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Falconer, Thomas" sort="Falconer, Thomas" uniqKey="Falconer T" first="Thomas" last="Falconer">Thomas Falconer</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Fernandez Bertolin, Sergio" sort="Fernandez Bertolin, Sergio" uniqKey="Fernandez Bertolin S" first="Sergio" last="Fernandez-Bertolin">Sergio Fernandez-Bertolin</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gao, Weihua" sort="Gao, Weihua" uniqKey="Gao W" first="Weihua" last="Gao">Weihua Gao</name><affiliation wicri:level="2"><nlm:affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Health Economics and Outcomes Research, AbbVie, North Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Golozar, Asieh" sort="Golozar, Asieh" uniqKey="Golozar A" first="Asieh" last="Golozar">Asieh Golozar</name><affiliation wicri:level="2"><nlm:affiliation>Pharmacoepidemiology, Regeneron, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pharmacoepidemiology, Regeneron, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hardin, Jill" sort="Hardin, Jill" uniqKey="Hardin J" first="Jill" last="Hardin">Jill Hardin</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Hripcsak, George" sort="Hripcsak, George" uniqKey="Hripcsak G" first="George" last="Hripcsak">George Hripcsak</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="2"><nlm:affiliation>New York-Presbyterian Hospital, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York-Presbyterian Hospital, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Huser, Vojtech" sort="Huser, Vojtech" uniqKey="Huser V" first="Vojtech" last="Huser">Vojtech Huser</name><affiliation wicri:level="2"><nlm:affiliation>National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Library of Medicine, National Institutes of Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jeon, Hokyun" sort="Jeon, Hokyun" uniqKey="Jeon H" first="Hokyun" last="Jeon">Hokyun Jeon</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Jing, Yonghua" sort="Jing, Yonghua" uniqKey="Jing Y" first="Yonghua" last="Jing">Yonghua Jing</name><affiliation wicri:level="2"><nlm:affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Health Economics and Outcomes Research, AbbVie, North Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Jung, Chi Young" sort="Jung, Chi Young" uniqKey="Jung C" first="Chi Young" last="Jung">Chi Young Jung</name><affiliation wicri:level="1"><nlm:affiliation>Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu</wicri:regionArea><wicri:noRegion>Daegu</wicri:noRegion></affiliation></author><author><name sortKey="Kaas Hansen, Benjamin Skov" sort="Kaas Hansen, Benjamin Skov" uniqKey="Kaas Hansen B" first="Benjamin Skov" last="Kaas-Hansen">Benjamin Skov Kaas-Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Pharmacology Unit, Zealand University Hospital, Køge, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Clinical Pharmacology Unit, Zealand University Hospital, Køge</wicri:regionArea><wicri:noRegion>Køge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:affiliation>NNF Centre for Protein Research, University of Copenhagen, København, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>NNF Centre for Protein Research, University of Copenhagen, København</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Kaduk, Denys" sort="Kaduk, Denys" uniqKey="Kaduk D" first="Denys" last="Kaduk">Denys Kaduk</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv</wicri:regionArea><wicri:noRegion>Kharkiv</wicri:noRegion></affiliation></author><author><name sortKey="Kent, Seamus" sort="Kent, Seamus" uniqKey="Kent S" first="Seamus" last="Kent">Seamus Kent</name><affiliation wicri:level="3"><nlm:affiliation>Science Policy and Research, National Institute for Health and Care Excellence, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Science Policy and Research, National Institute for Health and Care Excellence, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Kim, Yeesuk" sort="Kim, Yeesuk" uniqKey="Kim Y" first="Yeesuk" last="Kim">Yeesuk Kim</name><affiliation wicri:level="3"><nlm:affiliation>Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kolovos, Spyros" sort="Kolovos, Spyros" uniqKey="Kolovos S" first="Spyros" last="Kolovos">Spyros Kolovos</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lane, Jennifer C E" sort="Lane, Jennifer C E" uniqKey="Lane J" first="Jennifer C E" last="Lane">Jennifer C E. Lane</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lee, Hyejin" sort="Lee, Hyejin" uniqKey="Lee H" first="Hyejin" last="Lee">Hyejin Lee</name><affiliation wicri:level="1"><nlm:affiliation>Bigdata Department, Health Insurance Review & Assessment Service, Wonju, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Bigdata Department, Health Insurance Review & Assessment Service, Wonju</wicri:regionArea><wicri:noRegion>Wonju</wicri:noRegion></affiliation></author><author><name sortKey="Lynch, Kristine E" sort="Lynch, Kristine E" uniqKey="Lynch K" first="Kristine E" last="Lynch">Kristine E. Lynch</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterans Affairs, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Makadia, Rupa" sort="Makadia, Rupa" uniqKey="Makadia R" first="Rupa" last="Makadia">Rupa Makadia</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Matheny, Michael E" sort="Matheny, Michael E" uniqKey="Matheny M" first="Michael E" last="Matheny">Michael E. Matheny</name><affiliation wicri:level="2"><nlm:affiliation>GRECC, Tennessee Valley Healthcare System VA, Nashville, TN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>GRECC, Tennessee Valley Healthcare System VA, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Mehta, Paras P" sort="Mehta, Paras P" uniqKey="Mehta P" first="Paras P" last="Mehta">Paras P. Mehta</name><affiliation wicri:level="2"><nlm:affiliation>College of Medicine-Tucson, University of Arizona, Tucson, AZ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Medicine-Tucson, University of Arizona, Tucson, AZ</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Morales, Daniel R" sort="Morales, Daniel R" uniqKey="Morales D" first="Daniel R" last="Morales">Daniel R. Morales</name><affiliation wicri:level="1"><nlm:affiliation>Division of Population Health and Genomics, University of Dundee, Dundee, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health and Genomics, University of Dundee, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Natarajan, Karthik" sort="Natarajan, Karthik" uniqKey="Natarajan K" first="Karthik" last="Natarajan">Karthik Natarajan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="2"><nlm:affiliation>New York-Presbyterian Hospital, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York-Presbyterian Hospital, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Nyberg, Fredrik" sort="Nyberg, Fredrik" uniqKey="Nyberg F" first="Fredrik" last="Nyberg">Fredrik Nyberg</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Ostropolets, Anna" sort="Ostropolets, Anna" uniqKey="Ostropolets A" first="Anna" last="Ostropolets">Anna Ostropolets</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Park, Rae Woong" sort="Park, Rae Woong" uniqKey="Park R" first="Rae Woong" last="Park">Rae Woong Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Park, Jimyung" sort="Park, Jimyung" uniqKey="Park J" first="Jimyung" last="Park">Jimyung Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Posada, Jose D" sort="Posada, Jose D" uniqKey="Posada J" first="Jose D" last="Posada">Jose D. Posada</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, School of Medicine, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Prats Uribe, Albert" sort="Prats Uribe, Albert" uniqKey="Prats Uribe A" first="Albert" last="Prats-Uribe">Albert Prats-Uribe</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Rao, Gowtham" sort="Rao, Gowtham" uniqKey="Rao G" first="Gowtham" last="Rao">Gowtham Rao</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Reich, Christian" sort="Reich, Christian" uniqKey="Reich C" first="Christian" last="Reich">Christian Reich</name><affiliation wicri:level="2"><nlm:affiliation>Real World Solutions, IQVIA, Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Real World Solutions, IQVIA, Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rho, Yeunsook" sort="Rho, Yeunsook" uniqKey="Rho Y" first="Yeunsook" last="Rho">Yeunsook Rho</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Rijnbeek, Peter" sort="Rijnbeek, Peter" uniqKey="Rijnbeek P" first="Peter" last="Rijnbeek">Peter Rijnbeek</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Schilling, Lisa M" sort="Schilling, Lisa M" uniqKey="Schilling L" first="Lisa M" last="Schilling">Lisa M. Schilling</name><affiliation wicri:level="2"><nlm:affiliation>Data Science to Patient Value Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Data Science to Patient Value Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Schuemie, Martijn" sort="Schuemie, Martijn" uniqKey="Schuemie M" first="Martijn" last="Schuemie">Martijn Schuemie</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shah, Nigam H" sort="Shah, Nigam H" uniqKey="Shah N" first="Nigam H" last="Shah">Nigam H. Shah</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, School of Medicine, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Shoaibi, Azza" sort="Shoaibi, Azza" uniqKey="Shoaibi A" first="Azza" last="Shoaibi">Azza Shoaibi</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Song, Seokyoung" sort="Song, Seokyoung" uniqKey="Song S" first="Seokyoung" last="Song">Seokyoung Song</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anesthesiology and Pain Medicine, Catholic University of Daegu, School of Medicine, Gyeongsan, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Anesthesiology and Pain Medicine, Catholic University of Daegu, School of Medicine, Gyeongsan</wicri:regionArea><wicri:noRegion>Gyeongsan</wicri:noRegion></affiliation></author><author><name sortKey="Spotnitz, Matthew" sort="Spotnitz, Matthew" uniqKey="Spotnitz M" first="Matthew" last="Spotnitz">Matthew Spotnitz</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Suchard, Marc A" sort="Suchard, Marc A" uniqKey="Suchard M" first="Marc A" last="Suchard">Marc A. Suchard</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Swerdel, Joel N" sort="Swerdel, Joel N" uniqKey="Swerdel J" first="Joel N" last="Swerdel">Joel N. Swerdel</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Vizcaya, David" sort="Vizcaya, David" uniqKey="Vizcaya D" first="David" last="Vizcaya">David Vizcaya</name><affiliation wicri:level="3"><nlm:affiliation>Bayer Pharmaceuticals, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Bayer Pharmaceuticals, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Volpe, Salvatore" sort="Volpe, Salvatore" uniqKey="Volpe S" first="Salvatore" last="Volpe">Salvatore Volpe</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Wen, Haini" sort="Wen, Haini" uniqKey="Wen H" first="Haini" last="Wen">Haini Wen</name><affiliation wicri:level="1"><nlm:affiliation>Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Williams, Andrew E" sort="Williams, Andrew E" uniqKey="Williams A" first="Andrew E" last="Williams">Andrew E. Williams</name><affiliation wicri:level="2"><nlm:affiliation>Tufts Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Tufts Institute for Clinical Research and Health Policy Studies, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Yimer, Belay B" sort="Yimer, Belay B" uniqKey="Yimer B" first="Belay B" last="Yimer">Belay B. Yimer</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Zhang, Lin" sort="Zhang, Lin" uniqKey="Zhang L" first="Lin" last="Zhang">Lin Zhang</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Zhuk, Oleg" sort="Zhuk, Oleg" uniqKey="Zhuk O" first="Oleg" last="Zhuk">Oleg Zhuk</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Prieto Alhambra, Daniel" sort="Prieto Alhambra, Daniel" uniqKey="Prieto Alhambra D" first="Daniel" last="Prieto-Alhambra">Daniel Prieto-Alhambra</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK. daniel.prietoalhambra@ndorms.ox.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Ryan, Patrick" sort="Ryan, Patrick" uniqKey="Ryan P" first="Patrick" last="Ryan">Patrick Ryan</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33024121</idno><idno type="pmid">33024121</idno><idno type="doi">10.1038/s41467-020-18849-z</idno><idno type="pmc">PMC7538555</idno><idno type="wicri:Area/Main/Corpus">000265</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000265</idno><idno type="wicri:Area/Main/Curation">000265</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000265</idno><idno type="wicri:Area/Main/Exploration">000265</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.</title><author><name sortKey="Burn, Edward" sort="Burn, Edward" uniqKey="Burn E" first="Edward" last="Burn">Edward Burn</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="You, Seng Chan" sort="You, Seng Chan" uniqKey="You S" first="Seng Chan" last="You">Seng Chan You</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Sena, Anthony G" sort="Sena, Anthony G" uniqKey="Sena A" first="Anthony G" last="Sena">Anthony G. Sena</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Kostka, Kristin" sort="Kostka, Kristin" uniqKey="Kostka K" first="Kristin" last="Kostka">Kristin Kostka</name><affiliation wicri:level="2"><nlm:affiliation>Real World Solutions, IQVIA, Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Real World Solutions, IQVIA, Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Abedtash, Hamed" sort="Abedtash, Hamed" uniqKey="Abedtash H" first="Hamed" last="Abedtash">Hamed Abedtash</name><affiliation wicri:level="2"><nlm:affiliation>Eli Lilly and Company, Indianapolis, IN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Eli Lilly and Company, Indianapolis, IN</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Abrahao, Maria Tereza F" sort="Abrahao, Maria Tereza F" uniqKey="Abrahao M" first="Maria Tereza F" last="Abrahão">Maria Tereza F. Abrahão</name><affiliation wicri:level="4"><nlm:affiliation>Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.</nlm:affiliation><country xml:lang="fr">Brésil</country><wicri:regionArea>Faculty of Medicine, University of Sao Paulo, Sao Paulo</wicri:regionArea><placeName><settlement type="city">São Paulo</settlement><region type="state">État de São Paulo</region></placeName><orgName type="university">Université de São Paulo</orgName></affiliation></author><author><name sortKey="Alberga, Amanda" sort="Alberga, Amanda" uniqKey="Alberga A" first="Amanda" last="Alberga">Amanda Alberga</name><affiliation wicri:level="1"><nlm:affiliation>Observational Health Data Sciences and Informatics Network, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Observational Health Data Sciences and Informatics Network, Alberta</wicri:regionArea><wicri:noRegion>Alberta</wicri:noRegion></affiliation></author><author><name sortKey="Alghoul, Heba" sort="Alghoul, Heba" uniqKey="Alghoul H" first="Heba" last="Alghoul">Heba Alghoul</name><affiliation><nlm:affiliation>Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.</nlm:affiliation><wicri:noCountry code="subField">Palestine</wicri:noCountry></affiliation></author><author><name sortKey="Alser, Osaid" sort="Alser, Osaid" uniqKey="Alser O" first="Osaid" last="Alser">Osaid Alser</name><affiliation wicri:level="2"><nlm:affiliation>Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Massachusetts General Hospital, Harvard Medical School, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Alshammari, Thamir M" sort="Alshammari, Thamir M" uniqKey="Alshammari T" first="Thamir M" last="Alshammari">Thamir M. Alshammari</name><affiliation wicri:level="1"><nlm:affiliation>Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>Medication Safety Research Chair, King Saud University, Riyadh</wicri:regionArea><wicri:noRegion>Riyadh</wicri:noRegion></affiliation></author><author><name sortKey="Aragon, Maria" sort="Aragon, Maria" uniqKey="Aragon M" first="Maria" last="Aragon">Maria Aragon</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Areia, Carlos" sort="Areia, Carlos" uniqKey="Areia C" first="Carlos" last="Areia">Carlos Areia</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Banda, Juan M" sort="Banda, Juan M" uniqKey="Banda J" first="Juan M" last="Banda">Juan M. Banda</name><affiliation wicri:level="2"><nlm:affiliation>Department of Computer Science, Georgia State University, Atlanta, GA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Computer Science, Georgia State University, Atlanta, GA</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Cho, Jaehyeong" sort="Cho, Jaehyeong" uniqKey="Cho J" first="Jaehyeong" last="Cho">Jaehyeong Cho</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Culhane, Aedin C" sort="Culhane, Aedin C" uniqKey="Culhane A" first="Aedin C" last="Culhane">Aedin C. Culhane</name><affiliation wicri:level="2"><nlm:affiliation>Data Science, Dana-Farber Cancer Institute. Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Data Science, Dana-Farber Cancer Institute. Biostatistics, Harvard TH Chan School of Public Health, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Davydov, Alexander" sort="Davydov, Alexander" uniqKey="Davydov A" first="Alexander" last="Davydov">Alexander Davydov</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk, Belarus.</nlm:affiliation><country xml:lang="fr">Biélorussie</country><wicri:regionArea>Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk</wicri:regionArea><wicri:noRegion>Minsk</wicri:noRegion></affiliation></author><author><name sortKey="Defalco, Frank J" sort="Defalco, Frank J" uniqKey="Defalco F" first="Frank J" last="Defalco">Frank J. Defalco</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Duarte Salles, Talita" sort="Duarte Salles, Talita" uniqKey="Duarte Salles T" first="Talita" last="Duarte-Salles">Talita Duarte-Salles</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Duvall, Scott" sort="Duvall, Scott" uniqKey="Duvall S" first="Scott" last="Duvall">Scott Duvall</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterans Affairs, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Falconer, Thomas" sort="Falconer, Thomas" uniqKey="Falconer T" first="Thomas" last="Falconer">Thomas Falconer</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Fernandez Bertolin, Sergio" sort="Fernandez Bertolin, Sergio" uniqKey="Fernandez Bertolin S" first="Sergio" last="Fernandez-Bertolin">Sergio Fernandez-Bertolin</name><affiliation wicri:level="3"><nlm:affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gao, Weihua" sort="Gao, Weihua" uniqKey="Gao W" first="Weihua" last="Gao">Weihua Gao</name><affiliation wicri:level="2"><nlm:affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Health Economics and Outcomes Research, AbbVie, North Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Golozar, Asieh" sort="Golozar, Asieh" uniqKey="Golozar A" first="Asieh" last="Golozar">Asieh Golozar</name><affiliation wicri:level="2"><nlm:affiliation>Pharmacoepidemiology, Regeneron, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pharmacoepidemiology, Regeneron, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hardin, Jill" sort="Hardin, Jill" uniqKey="Hardin J" first="Jill" last="Hardin">Jill Hardin</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Hripcsak, George" sort="Hripcsak, George" uniqKey="Hripcsak G" first="George" last="Hripcsak">George Hripcsak</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="2"><nlm:affiliation>New York-Presbyterian Hospital, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York-Presbyterian Hospital, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Huser, Vojtech" sort="Huser, Vojtech" uniqKey="Huser V" first="Vojtech" last="Huser">Vojtech Huser</name><affiliation wicri:level="2"><nlm:affiliation>National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Library of Medicine, National Institutes of Health, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Jeon, Hokyun" sort="Jeon, Hokyun" uniqKey="Jeon H" first="Hokyun" last="Jeon">Hokyun Jeon</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Jing, Yonghua" sort="Jing, Yonghua" uniqKey="Jing Y" first="Yonghua" last="Jing">Yonghua Jing</name><affiliation wicri:level="2"><nlm:affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Health Economics and Outcomes Research, AbbVie, North Chicago, IL</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Jung, Chi Young" sort="Jung, Chi Young" uniqKey="Jung C" first="Chi Young" last="Jung">Chi Young Jung</name><affiliation wicri:level="1"><nlm:affiliation>Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu</wicri:regionArea><wicri:noRegion>Daegu</wicri:noRegion></affiliation></author><author><name sortKey="Kaas Hansen, Benjamin Skov" sort="Kaas Hansen, Benjamin Skov" uniqKey="Kaas Hansen B" first="Benjamin Skov" last="Kaas-Hansen">Benjamin Skov Kaas-Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Pharmacology Unit, Zealand University Hospital, Køge, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Clinical Pharmacology Unit, Zealand University Hospital, Køge</wicri:regionArea><wicri:noRegion>Køge</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:affiliation>NNF Centre for Protein Research, University of Copenhagen, København, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>NNF Centre for Protein Research, University of Copenhagen, København</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Kaduk, Denys" sort="Kaduk, Denys" uniqKey="Kaduk D" first="Denys" last="Kaduk">Denys Kaduk</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv</wicri:regionArea><wicri:noRegion>Kharkiv</wicri:noRegion></affiliation></author><author><name sortKey="Kent, Seamus" sort="Kent, Seamus" uniqKey="Kent S" first="Seamus" last="Kent">Seamus Kent</name><affiliation wicri:level="3"><nlm:affiliation>Science Policy and Research, National Institute for Health and Care Excellence, London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Science Policy and Research, National Institute for Health and Care Excellence, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Kim, Yeesuk" sort="Kim, Yeesuk" uniqKey="Kim Y" first="Yeesuk" last="Kim">Yeesuk Kim</name><affiliation wicri:level="3"><nlm:affiliation>Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kolovos, Spyros" sort="Kolovos, Spyros" uniqKey="Kolovos S" first="Spyros" last="Kolovos">Spyros Kolovos</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lane, Jennifer C E" sort="Lane, Jennifer C E" uniqKey="Lane J" first="Jennifer C E" last="Lane">Jennifer C E. Lane</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Lee, Hyejin" sort="Lee, Hyejin" uniqKey="Lee H" first="Hyejin" last="Lee">Hyejin Lee</name><affiliation wicri:level="1"><nlm:affiliation>Bigdata Department, Health Insurance Review & Assessment Service, Wonju, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Bigdata Department, Health Insurance Review & Assessment Service, Wonju</wicri:regionArea><wicri:noRegion>Wonju</wicri:noRegion></affiliation></author><author><name sortKey="Lynch, Kristine E" sort="Lynch, Kristine E" uniqKey="Lynch K" first="Kristine E" last="Lynch">Kristine E. Lynch</name><affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterans Affairs, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Utah School of Medicine, Salt Lake City, UT</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Makadia, Rupa" sort="Makadia, Rupa" uniqKey="Makadia R" first="Rupa" last="Makadia">Rupa Makadia</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Matheny, Michael E" sort="Matheny, Michael E" uniqKey="Matheny M" first="Michael E" last="Matheny">Michael E. Matheny</name><affiliation wicri:level="2"><nlm:affiliation>GRECC, Tennessee Valley Healthcare System VA, Nashville, TN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>GRECC, Tennessee Valley Healthcare System VA, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Mehta, Paras P" sort="Mehta, Paras P" uniqKey="Mehta P" first="Paras P" last="Mehta">Paras P. Mehta</name><affiliation wicri:level="2"><nlm:affiliation>College of Medicine-Tucson, University of Arizona, Tucson, AZ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>College of Medicine-Tucson, University of Arizona, Tucson, AZ</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Morales, Daniel R" sort="Morales, Daniel R" uniqKey="Morales D" first="Daniel R" last="Morales">Daniel R. Morales</name><affiliation wicri:level="1"><nlm:affiliation>Division of Population Health and Genomics, University of Dundee, Dundee, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Population Health and Genomics, University of Dundee, Dundee</wicri:regionArea><wicri:noRegion>Dundee</wicri:noRegion></affiliation></author><author><name sortKey="Natarajan, Karthik" sort="Natarajan, Karthik" uniqKey="Natarajan K" first="Karthik" last="Natarajan">Karthik Natarajan</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="2"><nlm:affiliation>New York-Presbyterian Hospital, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>New York-Presbyterian Hospital, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Nyberg, Fredrik" sort="Nyberg, Fredrik" uniqKey="Nyberg F" first="Fredrik" last="Nyberg">Fredrik Nyberg</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="Ostropolets, Anna" sort="Ostropolets, Anna" uniqKey="Ostropolets A" first="Anna" last="Ostropolets">Anna Ostropolets</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Park, Rae Woong" sort="Park, Rae Woong" uniqKey="Park R" first="Rae Woong" last="Park">Rae Woong Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Park, Jimyung" sort="Park, Jimyung" uniqKey="Park J" first="Jimyung" last="Park">Jimyung Park</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon</wicri:regionArea><wicri:noRegion>Suwon</wicri:noRegion></affiliation></author><author><name sortKey="Posada, Jose D" sort="Posada, Jose D" uniqKey="Posada J" first="Jose D" last="Posada">Jose D. Posada</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, School of Medicine, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Prats Uribe, Albert" sort="Prats Uribe, Albert" uniqKey="Prats Uribe A" first="Albert" last="Prats-Uribe">Albert Prats-Uribe</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Rao, Gowtham" sort="Rao, Gowtham" uniqKey="Rao G" first="Gowtham" last="Rao">Gowtham Rao</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Reich, Christian" sort="Reich, Christian" uniqKey="Reich C" first="Christian" last="Reich">Christian Reich</name><affiliation wicri:level="2"><nlm:affiliation>Real World Solutions, IQVIA, Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Real World Solutions, IQVIA, Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rho, Yeunsook" sort="Rho, Yeunsook" uniqKey="Rho Y" first="Yeunsook" last="Rho">Yeunsook Rho</name><affiliation wicri:level="4"><nlm:affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Rijnbeek, Peter" sort="Rijnbeek, Peter" uniqKey="Rijnbeek P" first="Peter" last="Rijnbeek">Peter Rijnbeek</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Schilling, Lisa M" sort="Schilling, Lisa M" uniqKey="Schilling L" first="Lisa M" last="Schilling">Lisa M. Schilling</name><affiliation wicri:level="2"><nlm:affiliation>Data Science to Patient Value Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Data Science to Patient Value Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO</wicri:regionArea><placeName><region type="state">Colorado</region></placeName></affiliation></author><author><name sortKey="Schuemie, Martijn" sort="Schuemie, Martijn" uniqKey="Schuemie M" first="Martijn" last="Schuemie">Martijn Schuemie</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Shah, Nigam H" sort="Shah, Nigam H" uniqKey="Shah N" first="Nigam H" last="Shah">Nigam H. Shah</name><affiliation wicri:level="4"><nlm:affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, School of Medicine, Stanford University, Stanford, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Shoaibi, Azza" sort="Shoaibi, Azza" uniqKey="Shoaibi A" first="Azza" last="Shoaibi">Azza Shoaibi</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Song, Seokyoung" sort="Song, Seokyoung" uniqKey="Song S" first="Seokyoung" last="Song">Seokyoung Song</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anesthesiology and Pain Medicine, Catholic University of Daegu, School of Medicine, Gyeongsan, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Anesthesiology and Pain Medicine, Catholic University of Daegu, School of Medicine, Gyeongsan</wicri:regionArea><wicri:noRegion>Gyeongsan</wicri:noRegion></affiliation></author><author><name sortKey="Spotnitz, Matthew" sort="Spotnitz, Matthew" uniqKey="Spotnitz M" first="Matthew" last="Spotnitz">Matthew Spotnitz</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Suchard, Marc A" sort="Suchard, Marc A" uniqKey="Suchard M" first="Marc A" last="Suchard">Marc A. Suchard</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Swerdel, Joel N" sort="Swerdel, Joel N" uniqKey="Swerdel J" first="Joel N" last="Swerdel">Joel N. Swerdel</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Vizcaya, David" sort="Vizcaya, David" uniqKey="Vizcaya D" first="David" last="Vizcaya">David Vizcaya</name><affiliation wicri:level="3"><nlm:affiliation>Bayer Pharmaceuticals, Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Bayer Pharmaceuticals, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Volpe, Salvatore" sort="Volpe, Salvatore" uniqKey="Volpe S" first="Salvatore" last="Volpe">Salvatore Volpe</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biomedical Informatics, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Wen, Haini" sort="Wen, Haini" uniqKey="Wen H" first="Haini" last="Wen">Haini Wen</name><affiliation wicri:level="1"><nlm:affiliation>Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Williams, Andrew E" sort="Williams, Andrew E" uniqKey="Williams A" first="Andrew E" last="Williams">Andrew E. Williams</name><affiliation wicri:level="2"><nlm:affiliation>Tufts Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Tufts Institute for Clinical Research and Health Policy Studies, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Yimer, Belay B" sort="Yimer, Belay B" uniqKey="Yimer B" first="Belay B" last="Yimer">Belay B. Yimer</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Zhang, Lin" sort="Zhang, Lin" uniqKey="Zhang L" first="Lin" last="Zhang">Lin Zhang</name><affiliation wicri:level="3"><nlm:affiliation>School of Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Zhuk, Oleg" sort="Zhuk, Oleg" uniqKey="Zhuk O" first="Oleg" last="Zhuk">Oleg Zhuk</name><affiliation wicri:level="2"><nlm:affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Odysseus Data Services, Inc., Cambridge, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Prieto Alhambra, Daniel" sort="Prieto Alhambra, Daniel" uniqKey="Prieto Alhambra D" first="Daniel" last="Prieto-Alhambra">Daniel Prieto-Alhambra</name><affiliation wicri:level="4"><nlm:affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK. daniel.prietoalhambra@ndorms.ox.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Ryan, Patrick" sort="Ryan, Patrick" uniqKey="Ryan P" first="Patrick" last="Ryan">Patrick Ryan</name><affiliation wicri:level="2"><nlm:affiliation>Janssen Research and Development, Titusville, NJ, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Janssen Research and Development, Titusville, NJ</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation><affiliation wicri:level="4"><nlm:affiliation>Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Age Factors (MeSH)</term><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>COVID-19 (MeSH)</term><term>Cohort Studies (MeSH)</term><term>Comorbidity (MeSH)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (epidemiology)</term><term>Female (MeSH)</term><term>Hospitalization (MeSH)</term><term>Humans (MeSH)</term><term>Influenza, Human (drug therapy)</term><term>Influenza, Human (epidemiology)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (drug therapy)</term><term>Pneumonia, Viral (epidemiology)</term><term>Prevalence (MeSH)</term><term>Republic of Korea (epidemiology)</term><term>Sex Factors (MeSH)</term><term>Spain (epidemiology)</term><term>United States (epidemiology)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Comorbidité (MeSH)</term><term>Espagne (épidémiologie)</term><term>Facteurs sexuels (MeSH)</term><term>Facteurs âges (MeSH)</term><term>Femelle (MeSH)</term><term>Grippe humaine (traitement médicamenteux)</term><term>Grippe humaine (épidémiologie)</term><term>Hospitalisation (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Infections à coronavirus (épidémiologie)</term><term>Jeune adulte (MeSH)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (traitement médicamenteux)</term><term>Pneumopathie virale (épidémiologie)</term><term>Prévalence (MeSH)</term><term>République de Corée (épidémiologie)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>États-Unis (épidémiologie)</term><term>Études de cohortes (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Republic of Korea</term><term>Spain</term><term>United States</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Influenza, Human</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Influenza, Human</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grippe humaine</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term><term>Grippe humaine</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>République de Corée</term><term>États-Unis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>COVID-19</term><term>Cohort Studies</term><term>Comorbidity</term><term>Female</term><term>Hospitalization</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Prevalence</term><term>Sex Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Comorbidité</term><term>Facteurs sexuels</term><term>Facteurs âges</term><term>Femelle</term><term>Hospitalisation</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Pandémies</term><term>Prévalence</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études de cohortes</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term><term>États-Unis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33024121</PMID><DateCompleted><Year>2020</Year><Month>10</Month><Day>13</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>18</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2041-1723</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>10</Month><Day>06</Day></PubDate></JournalIssue><Title>Nature communications</Title><ISOAbbreviation>Nat Commun</ISOAbbreviation></Journal><ArticleTitle>Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.</ArticleTitle><Pagination><MedlinePgn>5009</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/s41467-020-18849-z</ELocationID><Abstract><AbstractText>Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Burn</LastName><ForeName>Edward</ForeName><Initials>E</Initials><Identifier Source="ORCID">0000-0002-9286-1128</Identifier><AffiliationInfo><Affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>You</LastName><ForeName>Seng Chan</ForeName><Initials>SC</Initials><Identifier Source="ORCID">0000-0002-5052-6399</Identifier><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sena</LastName><ForeName>Anthony G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kostka</LastName><ForeName>Kristin</ForeName><Initials>K</Initials><Identifier Source="ORCID">0000-0003-2595-8736</Identifier><AffiliationInfo><Affiliation>Real World Solutions, IQVIA, Cambridge, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abedtash</LastName><ForeName>Hamed</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0002-9139-5452</Identifier><AffiliationInfo><Affiliation>Eli Lilly and Company, Indianapolis, IN, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abrahão</LastName><ForeName>Maria Tereza F</ForeName><Initials>MTF</Initials><Identifier Source="ORCID">0000-0003-2701-670X</Identifier><AffiliationInfo><Affiliation>Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alberga</LastName><ForeName>Amanda</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Observational Health Data Sciences and Informatics Network, Alberta, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alghoul</LastName><ForeName>Heba</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0001-8234-5843</Identifier><AffiliationInfo><Affiliation>Faculty of Medicine, Islamic University of Gaza, Gaza, Palestine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alser</LastName><ForeName>Osaid</ForeName><Initials>O</Initials><Identifier Source="ORCID">0000-0001-6743-803X</Identifier><AffiliationInfo><Affiliation>Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alshammari</LastName><ForeName>Thamir M</ForeName><Initials>TM</Initials><AffiliationInfo><Affiliation>Medication Safety Research Chair, King Saud University, Riyadh, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aragon</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Areia</LastName><ForeName>Carlos</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0002-4668-7069</Identifier><AffiliationInfo><Affiliation>Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Banda</LastName><ForeName>Juan M</ForeName><Initials>JM</Initials><Identifier Source="ORCID">0000-0001-8499-824X</Identifier><AffiliationInfo><Affiliation>Department of Computer Science, Georgia State University, Atlanta, GA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cho</LastName><ForeName>Jaehyeong</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Culhane</LastName><ForeName>Aedin C</ForeName><Initials>AC</Initials><Identifier Source="ORCID">0000-0002-1395-9734</Identifier><AffiliationInfo><Affiliation>Data Science, Dana-Farber Cancer Institute. Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Davydov</LastName><ForeName>Alexander</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department for Microbiology, Virology and Immunology, Belarusian State Medical University, Minsk, Belarus.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>DeFalco</LastName><ForeName>Frank J</ForeName><Initials>FJ</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duarte-Salles</LastName><ForeName>Talita</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>DuVall</LastName><ForeName>Scott</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Falconer</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernandez-Bertolin</LastName><ForeName>Sergio</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Weihua</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Golozar</LastName><ForeName>Asieh</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0002-4243-155X</Identifier><AffiliationInfo><Affiliation>Pharmacoepidemiology, Regeneron, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Johns Hopkins School of Public, Baltimore, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hardin</LastName><ForeName>Jill</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hripcsak</LastName><ForeName>George</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>New York-Presbyterian Hospital, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Huser</LastName><ForeName>Vojtech</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jeon</LastName><ForeName>Hokyun</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0002-6220-4207</Identifier><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jing</LastName><ForeName>Yonghua</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Health Economics and Outcomes Research, AbbVie, North Chicago, IL, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jung</LastName><ForeName>Chi Young</ForeName><Initials>CY</Initials><AffiliationInfo><Affiliation>Division of Respiratory and Critical Care Medicine, Department of Internal Medicine, Daegu Catholic University Medical Center, Daegu, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaas-Hansen</LastName><ForeName>Benjamin Skov</ForeName><Initials>BS</Initials><Identifier Source="ORCID">0000-0003-1023-0371</Identifier><AffiliationInfo><Affiliation>Clinical Pharmacology Unit, Zealand University Hospital, Køge, Denmark.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>NNF Centre for Protein Research, University of Copenhagen, København, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaduk</LastName><ForeName>Denys</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Pediatrics № 2, V. N. Karazin Kharkiv National University, Kharkiv, Ukraine.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kent</LastName><ForeName>Seamus</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Science Policy and Research, National Institute for Health and Care Excellence, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Yeesuk</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0003-4956-0693</Identifier><AffiliationInfo><Affiliation>Department of Orthopaedic Surgery, College of Medicine, Hanyang University, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolovos</LastName><ForeName>Spyros</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lane</LastName><ForeName>Jennifer C E</ForeName><Initials>JCE</Initials><Identifier Source="ORCID">0000-0002-1729-8654</Identifier><AffiliationInfo><Affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Hyejin</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Bigdata Department, Health Insurance Review & Assessment Service, Wonju, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lynch</LastName><ForeName>Kristine E</ForeName><Initials>KE</Initials><AffiliationInfo><Affiliation>Department of Veterans Affairs, Salt Lake City, UT, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of Utah School of Medicine, Salt Lake City, UT, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Makadia</LastName><ForeName>Rupa</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Matheny</LastName><ForeName>Michael E</ForeName><Initials>ME</Initials><AffiliationInfo><Affiliation>GRECC, Tennessee Valley Healthcare System VA, Nashville, TN, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mehta</LastName><ForeName>Paras P</ForeName><Initials>PP</Initials><Identifier Source="ORCID">0000-0002-0233-9871</Identifier><AffiliationInfo><Affiliation>College of Medicine-Tucson, University of Arizona, Tucson, AZ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morales</LastName><ForeName>Daniel R</ForeName><Initials>DR</Initials><AffiliationInfo><Affiliation>Division of Population Health and Genomics, University of Dundee, Dundee, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Natarajan</LastName><ForeName>Karthik</ForeName><Initials>K</Initials><Identifier Source="ORCID">0000-0002-9066-9431</Identifier><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>New York-Presbyterian Hospital, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nyberg</LastName><ForeName>Fredrik</ForeName><Initials>F</Initials><Identifier Source="ORCID">0000-0003-0892-5668</Identifier><AffiliationInfo><Affiliation>School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ostropolets</LastName><ForeName>Anna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Park</LastName><ForeName>Rae Woong</ForeName><Initials>RW</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Park</LastName><ForeName>Jimyung</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0002-6998-2546</Identifier><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Posada</LastName><ForeName>Jose D</ForeName><Initials>JD</Initials><Identifier Source="ORCID">0000-0003-3864-0241</Identifier><AffiliationInfo><Affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prats-Uribe</LastName><ForeName>Albert</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0003-1202-9153</Identifier><AffiliationInfo><Affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rao</LastName><ForeName>Gowtham</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Reich</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Real World Solutions, IQVIA, Cambridge, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rho</LastName><ForeName>Yeunsook</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rijnbeek</LastName><ForeName>Peter</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schilling</LastName><ForeName>Lisa M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Data Science to Patient Value Program, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schuemie</LastName><ForeName>Martijn</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shah</LastName><ForeName>Nigam H</ForeName><Initials>NH</Initials><Identifier Source="ORCID">0000-0001-9385-7158</Identifier><AffiliationInfo><Affiliation>Department of Medicine, School of Medicine, Stanford University, Stanford, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shoaibi</LastName><ForeName>Azza</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Seokyoung</ForeName><Initials>S</Initials><Identifier Source="ORCID">0000-0002-5653-7005</Identifier><AffiliationInfo><Affiliation>Department of Anesthesiology and Pain Medicine, Catholic University of Daegu, School of Medicine, Gyeongsan, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Spotnitz</LastName><ForeName>Matthew</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Suchard</LastName><ForeName>Marc A</ForeName><Initials>MA</Initials><Identifier Source="ORCID">0000-0001-9818-479X</Identifier><AffiliationInfo><Affiliation>Department of Biostatistics, UCLA Fielding School of Public Health, University of California, Los Angeles, CA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Swerdel</LastName><ForeName>Joel N</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Janssen Research and Development, Titusville, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vizcaya</LastName><ForeName>David</ForeName><Initials>D</Initials><Identifier Source="ORCID">0000-0003-0248-7636</Identifier><AffiliationInfo><Affiliation>Bayer Pharmaceuticals, Barcelona, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Volpe</LastName><ForeName>Salvatore</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Biomedical Informatics, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wen</LastName><ForeName>Haini</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Williams</LastName><ForeName>Andrew E</ForeName><Initials>AE</Initials><Identifier Source="ORCID">0000-0002-0692-412X</Identifier><AffiliationInfo><Affiliation>Tufts Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yimer</LastName><ForeName>Belay B</ForeName><Initials>BB</Initials><Identifier Source="ORCID">0000-0001-8621-6539</Identifier><AffiliationInfo><Affiliation>Centre for Epidemiology Versus Arthritis, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Lin</ForeName><Initials>L</Initials><Identifier Source="ORCID">0000-0002-2064-8440</Identifier><AffiliationInfo><Affiliation>School of Public Health, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhuk</LastName><ForeName>Oleg</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Odysseus Data Services, Inc., Cambridge, MA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prieto-Alhambra</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><Identifier Source="ORCID">0000-0002-3950-6346</Identifier><AffiliationInfo><Affiliation>Centre for Statistics in Medicine (CSM), Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDROMS), University of Oxford, Oxford, UK. daniel.prietoalhambra@ndorms.ox.ac.uk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ryan</LastName><ForeName>Patrick</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Janssen Research 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|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:33024121
|texte= Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:33024121" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidStanfordV1
| This area was generated with Dilib version V0.6.38. |  |